Development of MAST: A Microscopy-Based Antimicrobial Susceptibility Testing Platform
نویسندگان
چکیده
منابع مشابه
Verification of an Automated, Digital Dispensing Platform for At-Will Broth Microdilution-Based Antimicrobial Susceptibility Testing.
With rapid emergence of multidrug-resistant bacteria, there is often a need to perform susceptibility testing for less commonly used or newer antimicrobial agents. Such testing can often be performed only by using labor-intensive, manual dilution methods and lies outside the capacity of most clinical labs, necessitating reference laboratory testing and thereby delaying the availability of susce...
متن کاملHistory and development of antimicrobial susceptibility testing methodology.
Antimicrobial susceptibility testing (AST) is performed daily on bacterial isolates in clinical laboratories. The techniques employed are often taken for granted. This paper traces the history and development of some methods still in common use for routine AST, e.g. disc diffusion and agar dilution. It was quickly recognized by early investigators that there were many variables affecting the re...
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Cefoperazone is a new cephalosporin with a very wide spectrum of activity, including activity against Pseudomonas aeruginosa. It has less activity on enterococci and Acinetobacter. Of the 459 selected bacterial strains tested in this study, only 1.5% (7 strains and 6 genera) had minimum inhibitory concentrations of >128 ,ug/ml. For a minimum inhibitory concentration breakpoint of <32 p.g/ml (su...
متن کاملAntimicrobial susceptibility testing: a primer for clinicians.
Appropriate use of antimicrobials in health care continues to be a challenge. Reliable and reproducible antimicrobial susceptibility testing methods are necessary to provide the clinician with valuable information that can be translated into positive clinical outcomes at the bedside. However, there are nuances with these testing methods that, if unrecognized, could lead to misinterpretation of ...
متن کاملInstrumentation in antimicrobial susceptibility testing.
Studies in the 1960s demonstrated the problems of variability in susceptibility testing methods, especially those affecting the performance of disc diffusion procedures. These studies made apparent the need for standardization and resulted in more clearly defined performance limits for growth medium, incubation conditions, inoculum concentration, disc content for diffusion methods, the setting ...
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ژورنال
عنوان ژورنال: SLAS TECHNOLOGY: Translating Life Sciences Innovation
سال: 2017
ISSN: 2472-6303,2472-6311
DOI: 10.1177/2472630317727721